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The diagram shows the different places that therapies might affect. The bottom right hand side is the neural area. (illegible in the gif.) I say these therapies are in the future, but that future is coming fast! Therapies affecting the immune system are now in regular use. The other therapies (seemingly more aligned with symptoms) still block the flow of triggers if the circulatory model has any validity.

 

       QUERIES:
       What therapies stop the circulation/feedback? Does Progressive
       MS just keep going round?  Why?
       Relapsing/Remitting seems to have CNS/Neural exacerbations
       (with exacerbating neuroendocrine/chemical sysmptoms) but also
       underlying neuroendocrine/chemical pathology. Is this sometimes,
       or always?
 

       Are we looking under the lampost for the keys we dropped
       100 yards down the road, where it is dark? (Just because
       the functioning of the Autonomic system, for example,
       can't be measured easily.)
 

(the text of therapies in the model: put here for clarity)
THERAPIES:
       1.IMMUNE SYSTEM
       Interferon
       Betaseron
       Copolymer-1
 

       THERAPIES:
       2.NEURAL SYSTEM
       In the Future:
       Remyelination
       nerve growth (protein growth factors)
       transplantation (eg of foetal tissue)
 
 
 

       THERAPIES:
       3.CHEMICAL SYSTEM

       Steroids -Prednisone, anti-inflammatories, cortisone, ACTH (?)
       Anticholinergics - Donatab, Monodral, Probanthine
       Antidepressants - various, with varying specific and global effects.
       Antiepileptics - Tegretol, Dilantin
       Baclofen - for spasticity
       Carbamazepine - an anticonvulsant and for pain (plus capsaicin
       cream)
       Propanolol - a beta blocker, for tremor
       isoniazid, acetazolamide, conazepain
 

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